Friday, May 22, 2020

Research Ethics Animal And Clinical Research - 1188 Words

Research Ethics: Animal and Clinical Research When it comes to clinical research, many people think of clinical trials, but that’s only merely a small portion of a process towards a medical development involving a process call bench to the bedside. Clinical research outline scientific investigation involving animal or human subjects helping translate basic research into new treatments that would be valuable to patients. Clinical trials can contain a variety of research under the departments of physiology and pathophysiology, health services, and mental health. Furthermore, the process of developing new treatments from the bench to the bedside come in three stages: basic research, transitional research, and clinical research. First†¦show more content†¦Phase III Trials usually randomize compared trials, test efficacy compared to standard of care, once again test for further safety, and conclude to an effective dosage. Animal studies would be necessary based on the ani mals and the trials scientist are trying to conduct. Every animal is different, especially when compared to humans, but there are some in different animals that can help test based on the compound for the trials. Over time there has been numerous ethical violations in clinical research; some more significant than others. In 1906, when the Pure Food and Drug Act was passed, there were no regulations regarding the ethical use of human participants in research. There were no consumer regulations such as the Food and Drug Administration, Common Rule and Institutional Review Boards. One of the most significant events in research history involved human participants was the Nuremberg Code on December 9, 1946. American military opened criminal proceedings against several leading German physicians for their willing participation in crimes against humanity. German Physicians were charged for conducting medical experiments on thousands of concentration camp prisoners without their consent; in most of which the participants as a result either died or were permanently damaged physically. In conclusion of the trial, in 1948 the Nuremberg Code was established, making it known that participants should give consent.Show MoreRelatedA Research Study On Nutrition And Treatment Of Blood Glucose1621 Words   |  7 Pagesgranted the amount of research, time, effort, and money that went into the development of medications or medical treatment. When someone reaches for the aspirin bottle to relieve a pounding headache or that lifesaving injection of insulin used daily to treat and manage levels of blood glucose are both the end results of long and costly research. Without research the awareness of vitamin deficiencies, treatments for cancer, organ transplantation, and vaccines for humans and animals would cease to existRead MoreDrug Development Essay1537 Words   |  7 Pagesdevelopment This entire section on drug development highlights concerns which are very particular to the industry. They therefore lead to the implementation of CSR activities which are also very industry specific, although aspects such as animal testing and ethics in research can be shared by other industries such as the cosmetics industry, or the medical device sector for instance. Need for RD and innovation Today, the need for RD and innovation is great, maybe greater than ever. In the developed worldRead MoreAll Animals Are Equal Essay1744 Words   |  7 Pagesoccur each day on the issues of animal cruelty and human rights, but when the issues are put together which will reign over the other? 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Accounts of anxiety disorders, changes in behavior, hormone levels, and the amount of pain animals endure now drive the conversation regarding reforming animal testing practices. It is also noted that the predictive value of animal models do not translate into clinical success. The majority of animal research does not lead to improving human health. Most argue the use of animals overall is a needlessRead MoreProfessional Practice Issues Of Health Care Essay1072 Words   |  5 PagesProfessional Practice Issues in Health Care - Ethics Introduction Medical ethics play a huge role in the health care industry. A crucial part of a health care professional s role is to apply appropriate ethical guidelines into clinical settings. Due to its importance there is unlimited amount of references available in different forms regarding to this specific topic, however, the quality, reliability and relevance of each reference can remain questioned and requires further consideration. InRead MoreEthics of the Nuremberg Code Essay1065 Words   |  5 Pageswithfifteen of twenty-three German physicians and research scientist-physicians found guilty of criminal human experimentation projects. The trial court attempted to establish a set of principles of human experimentation that could serve as a code of research ethics. The result was the Nuremberg Code, which attempted to provide a natural law-based set of universal ethical principles. Looking beyond the Nuremberg Code and applying it to modern medical research ethics, there are many challenges that it posesRead MoreAnimal Experimentation : The End Of Animal Testing1118 Words   |  5 PagesThe experimentation of animals has been used for a multitude of years for research to advance a scientific understanding of a living organism. To this day animals are being tested on for the use of human products. In 3D-printing human skin: The end of animal testing? by Jessica Mendoza, Speculative Philosophy, the Troubled Middle, and the Ethics of Animal Experimentation by Strachan Donnelley, â€Å"Animals and Medical Science: A Vision of a New Era† by David O. Wiebers, Cruelty-free cosmetics benefitRead MoreEthical And Scientific Considerations Regarding Animal Testing And Research759 Words   |  4 PagesConsiderations Regarding Animal Testing and Research. The Principles of Humane Experimental Technique, which emphasized reduction, refinement, and replacement of animal use, principles, many scientists referred to the three R’s. These principles encouraged research ers to work to cut down the figure of animals utilized in experiments to the minimum considered necessary, refine or limit the pain and distress to which animals are exposed, and replace the use of animals with non-animal alternatives when possible

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